Clinical evaluation of deep learning-based automatic clinical target volume segmentation: a single-institution multi-site tumor experience.

Journal: La Radiologia medica
Published Date:

Abstract

PURPOSE: The large variability in tumor appearance and shape makes manual delineation of the clinical target volume (CTV) time-consuming, and the results depend on the oncologists' experience. Whereas deep learning techniques have allowed oncologists to automate the CTV delineation, multi-site tumor analysis is often lacking in the literature. This study aimed to evaluate the deep learning models that automatically contour CTVs of tumors at various sites on computed tomography (CT) images from objective and subjective perspectives.

Authors

  • Zhen Hou
    Institute of Medical Information & Library, Chinese Academy of Medical Sciences, Beijing, China.
  • Shanbao Gao
    The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, Jiangsu, China.
  • Juan Liu
    Key State Laboratory of Software Engineering, School of Computer, Wuhan University, Wuhan 430072, PR China. Electronic address: liujuan@whu.edu.cn.
  • Yicai Yin
    The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, Jiangsu, China.
  • Ling Zhang
  • Yongchao Han
    The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, Jiangsu, China.
  • Jing Yan
    Department of Neurology, Shanghai Pudong New Area People's Hospital, Shanghai, China.
  • Shuangshuang Li
    Guangdong Key Laboratory of Intelligent Information Processing and Shenzhen Key Laboratory of Media Security, Shenzhen University, Shenzhen 518060, China. Electronic address: lishuangshuang2016@email.szu.edu.cn.