Platelet-rich plasma inhibits Wnt/β-catenin signaling in rabbit cartilage cells activated by IL-1β.

Journal: International immunopharmacology
PMID: 29291543

Abstract

OBJECTIVE: Platelet-rich plasma (PRP) has been reported to alleviate degenerative pathological damage to joint cartilage. This study aimed to investigate the effect of PRP on Wnt/β-catenin signaling in rabbit chondrocytes.

Authors

  • Jian Wu
    Department of Medical Technology, Jiangxi Medical College, Shangrao, Jiangxi, China.
  • Ji-Feng Huang
    Department of Orthopaedics, Wuhan General Hospital of Guangzhou Military Area Commands affiliated Southern Medical University, Wuhan, China.
  • Xing-Xing Qin
    Department of Orthopaedics, XianNing Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, XianNing 437100, China.
  • Feng Hu
    Department of Orthopaedics, XianNing Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, XianNing 437100, China.
  • Zhao-Fei Chen
    Department of Orthopaedics, XianNing Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, XianNing 437100, China.
  • Yong Zheng
    Physical Education Institute, China West Normal University, Nanchong, China.
  • Yan-Xi Liu
    Department of Orthopaedics, XianNing Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, XianNing 437100, China.
  • Xian-Hua Cai
    Southern Medical University, Guangzhou 510515, China; Department of Orthopaedics, Wuhan General Hospital of Guangzhou Military Area Commands affiliated Southern Medical University, Wuhan, China. Electronic address: wgcaixh@163.com.

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