Application of artificial intelligence in quantifying lung deposition dose of black carbon in people with exposure to ambient combustion particles.

Journal: Journal of exposure science & environmental epidemiology
PMID:

Abstract

BACKGROUND: Understanding lung deposition dose of black carbon is critical to fully reconcile epidemiological evidence of combustion particles induced health effects and inform the development of air quality metrics concerning black carbon. Macrophage carbon load (MaCL) is a novel cytology method that quantifies lung deposition dose of black carbon, however it has limited feasibility in large-scale epidemiological study due to the labor-intensive manual counting.

Authors

  • Menghui Jiang
    School of Medicine, University of New Mexico, Albuquerque, NM, USA.
  • Chelin Jamie Hu
    College of Nursing, University of New Mexico College of Nursing, Albuquerque, NM, USA.
  • Cassie L Rowe
    School of Medicine, University of New Mexico, Albuquerque, NM, USA.
  • Huining Kang
    School of Medicine, University of New Mexico, Albuquerque, NM, USA.
  • Xi Gong
    Department of Geography & Environmental Studies, University of New Mexico, Albuquerque, NM, USA.
  • Christopher P Dagucon
    Lung Cancer Program, Lovelace Biomedical Research Institute, Albuquerque, NM, USA.
  • Jialiang Wang
    School of Medicine, University of New Mexico, Albuquerque, NM, USA.
  • Yan Lin
  • Akshay Sood
    1 Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI. 2 Kidney and Urology Institute, Medanta, Medicity, Gurgaon, India. 3 Department of Anesthesiology, Medanta, Medicity, Gurgaon, India.
  • Yan Guo
    State Key Laboratory of Pathogen and Biosecurity, Beijing 100071, China.
  • Yiliang Zhu
    School of Medicine, University of New Mexico, Albuquerque, NM, USA.
  • Neil E Alexis
    Center for Environmental Medicine Asthma and Lung Biology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Frank D Gilliland
    Department of Preventive Medicine, University of Southern California, 2001 N. Soto Street, MC-9234, Los Angeles, CA, 90089, USA.
  • Steven A Belinsky
    University of New Mexico Comprehensive Cancer Center, Albuquerque, NM, USA.
  • Xiaozhong Yu
    College of Nursing, University of New Mexico College of Nursing, Albuquerque, NM, USA. XiYu@salud.unm.edu.
  • Shuguang Leng
    School of Medicine, University of New Mexico, Albuquerque, NM, USA. sleng@salud.unm.edu.