Lipid nanoparticles (LNPs) have gained significant attention thanks to their ability to encapsulate and deliver mRNA. Exploring a variety of lipid compositions and different preparation processes is essential for a better understanding of the mRNA en...
Nanomedicine requires smart delivery systems that are precise, robust, and universal. While liposomes are established vehicles in drug delivery, their full potential is challenged by limited stability, leakage, insufficient response, and limited insi...
Bacterial-mediated drug delivery has emerged as a promising strategy for disease treatment, leveraging bacteria's innate ability to penetrate biological barriers and target diseased tissues. However, existing bacteria-nanoparticle hybrid systems ofte...
International journal of pharmaceutics
Dec 5, 2025
Mathematical modeling is becoming increasingly important in the pharmaceutical industry. It supports the Quality by Design framework by aiding process understanding and examining the impact of critical material and process parameters on the critical ...
In cancer combination therapy, micro-robot systems that integrate multiple therapeutic functions have emerged as a key direction for overcoming the limitations of traditional treatments. This study proposes a magnetic thermosensitive hydrogel capsule...
International journal of pharmaceutics
Nov 25, 2025
Defining suspension stability can be extremely complex, but beyond critical during the formulation development of nano- and microsuspensions intended for long-acting injectables. As of now, the current practice is based on the trial-and-error approac...
Journal of materials science. Materials in medicine
Nov 21, 2025
Metal oxide nanomaterials play a central role in biomedical applications due to their unique physicochemical properties. In particular, various treatment methods such as drug delivery, hyperthermia therapy, radiation, and chemotherapy are used for th...
The traditional approach has significant limitations in designing and manufacturing high-performance micro-nanorobots with complex three-dimensional structures and response characteristics at the micro-nanoscale, making it difficult to meet practical...
Inspired by the perception and temperature regulation functionalities of human skin, multifunctional electronic skin (E-skin) for human motion detection and personal thermal management has attracted great attention. Here, we design an E-skin with str...
International journal of pharmaceutics
Nov 4, 2025
Liposomes have transformed drug delivery by enhancing the solubility, stability, and bioavailability of therapeutic agents, driving widespread clinical adoption and contributing to a rapidly expanding multi-billion-dollar market. However, despite the...
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