The effect of vitamin D supplementation on insulin resistance, visceral fat and adiponectin in vitamin D deficient women with polycystic ovary syndrome: a randomized placebo-controlled trial.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Published Date:

Abstract

INTRODUCTION: Low plasma 25-hydroxy-vitamin D (25OHD) is associated with polycystic ovary syndrome (PCOS). Vitamin D deficiency may contribute to the development of insulin resistance, visceral fat and low level of adiponectin which are common feature in PCOS women. This study aimed to evaluate the effect of vitamin D supplementation on insulin resistance, visceral fat, and adiponectin in hypovitaminosis D women with polycystic ovary syndrome.

Authors

  • Maryam Seyyed Abootorabi
    a Department of Nutrition, School of Medicine , Urmia University of Medical Sciences , Urmia , The Islamic Republic of Iran.
  • Parvin Ayremlou
    b Clinical Research Development Unit of Imam Khomeini Hospital, Urmia University of Medical Sciences , Urmia , The Islamic Republic of Iran.
  • Tahereh Behroozi-Lak
    c Reproductive Health Research Center, Department of Infertility , Urmia University of Medical Sciences , Urmia , The Islamic Republic of Iran.
  • Sakineh Nourisaeidlou
    d Food and Beverages Safety Research Center , Urmia University of Medical Sciences , Urmia , The Islamic Republic of Iran.