Differentiation Between Glioblastoma and Metastatic Disease on Conventional MRI Imaging Using 3D-Convolutional Neural Networks: Model Development and Validation.

Journal: Academic radiology
Published Date: Nov 17, 2023

Abstract

RATIONALE AND OBJECTIVES: Imaging-based differentiation between glioblastoma (GB) and brain metastases (BM) remains challenging. Our aim was to evaluate the performance of 3D-convolutional neural networks (CNN) to address this binary classification problem.

Authors

  • Girish Bathla
    Mayo Clinic Rochester, Minnesota, USA.
  • Durjoy Deb Dhruba
    Electrical and Computer Engineering, University of Iowa, 4016 Seamans Center for the Engineering Arts and Sciences, Iowa City, IA 52242 USA.
  • Yanan Liu
    College of Environmental Science and Engineering, Donghua University, 2999 North Renmin Road, Shanghai 201620, China.
  • Nam H Le
    College of Engineering, University of Iowa, Iowa City, IA, USA.
  • Neetu Soni
    University of Rochester Medical Center Rochester, New York, USA.
  • Honghai Zhang
    Iowa Institute for Biomedical Imaging, University of Iowa, Iowa City, IA 52242, USA.
  • Suyash Mohan
    Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104 (J.D.R., L.X., A.K., J.M.E., T.C., I.M.N., S.M., J.C.G.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (J.D.R., A.M.R.); Penn Image Computing and Science Laboratory, University of Pennsylvania, Philadelphia, Pa (X.L., J.W.); University of Pennsylvania Perelman School of Medicine, Philadelphia, Pa (M.T.D.); Mecklenburg Radiology Associates, Charlotte, NC (E.J.B.); Department of Radiology, University of Texas, Austin, Tex (R.N.B.); and Division of Nuclear Medicine and Clinical Molecular Imaging, Department of Radiology, University of Pennsylvania, Philadelphia, Pa (I.M.N.).
  • Douglas Roberts-Wolfe
    Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104 USA.
  • Saima Rathore
    DCIS, Pakistan Institute of Engineering and Applied Sciences, Islamabad, Pakistan; DCS&IT, University of Azad Jammu and Kashmir, Muzaffarabad, Azad Kashmir. Electronic address: saimarathore_2k6@yahoo.com.
  • Milan Sonka
    Department of Electrical and Computer Engineering, The University of Iowa, Iowa City, IA, 52242, United States; Department of Ophthalmology and Visual Sciences, The University of Iowa, Iowa City, IA, 52242, United States.
  • Sarv Priya
    The University of Iowa Iowa City, Iowa, USA.
  • Amit Agarwal

Keywords

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