Defining lower airway bacterial infection in children with chronic endobronchial disorders.

Journal: Pediatric pulmonology
Published Date: Dec 19, 2017

Abstract

BACKGROUND: Differentiating lower airway bacterial infection from possible upper airway contamination in children with endobronchial disorders undergoing bronchoalveolar lavage (BAL) is important for guiding management. A diagnostic bacterial load threshold based on inflammatory markers has been determined to differentiate infection from upper airway contamination in infants with cystic fibrosis, but not for children with protracted bacterial bronchitis (PBB), chronic suppurative lung disease (CSLD), or bronchiectasis.

Authors

  • Kim M Hare
    Child Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.
  • Susan J Pizzutto
    Child Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.
  • Anne B Chang
    Child Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.
  • Heidi C Smith-Vaughan
    Child Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.
  • Gabrielle B McCallum
    Child Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.
  • Jemima Beissbarth
    Child Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.
  • Lesley Versteegh
    Child Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.
  • Keith Grimwood
    School of Medicine, Griffith University, Gold Coast, Queensland, Australia.

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