AIMC Topic: Bronchoalveolar Lavage Fluid

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Single-Cell Sequencing-Guided Annotation of Rare Tumor Cells for Deep Learning-Based Cytopathologic Diagnosis of Early Lung Cancer.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Deep learning (DL) models for medical image analysis are majorly bottlenecked by the lack of well-annotated datasets. Bronchoalveolar lavage (BAL) is a minimally invasive procedure to diagnose lung cancer, but BAL cytology suffers from low sensitivit...

Automated recognition and segmentation of lung cancer cytological images based on deep learning.

PloS one
Compared with histological examination of lung cancer, cytology is less invasive and provides better preservation of complete morphology and detail. However, traditional cytological diagnosis requires an experienced pathologist to evaluate all sectio...

Integrating respiratory microbiome and host immune response through machine learning for respiratory tract infection diagnosis.

NPJ biofilms and microbiomes
At present, the diagnosis of lower respiratory tract infections (LRTIs) is difficult, and there is an urgent need for better diagnostic methods. This study enrolled 136 patients from 2020 to 2021 and collected bronchoalveolar lavage fluid (BALF) spec...

Deciphering the microbial landscape of lower respiratory tract infections: insights from metagenomics and machine learning.

Frontiers in cellular and infection microbiology
BACKGROUND: Lower respiratory tract infections represent prevalent ailments. Nonetheless, current comprehension of the microbial ecosystems within the lower respiratory tract remains incomplete and necessitates further comprehensive assessment. Lever...

Deep Learning Neural Network-Guided Detection of Asbestos Bodies in Bronchoalveolar Lavage Samples.

Acta cytologica
INTRODUCTION: Asbestos is a global occupational health hazard, and exposure to it by inhalation predisposes to interstitial as well as malignant pulmonary morbidity. Over time, asbestos fibers embedded in lung tissue can become coated with iron-rich ...

Leukocyte differentiation in bronchoalveolar lavage fluids using higher harmonic generation microscopy and deep learning.

PloS one
BACKGROUND: In diseases such as interstitial lung diseases (ILDs), patient diagnosis relies on diagnostic analysis of bronchoalveolar lavage fluid (BALF) and biopsies. Immunological BALF analysis includes differentiation of leukocytes by standard cyt...

Cytologic scoring of equine exercise-induced pulmonary hemorrhage: Performance of human experts and a deep learning-based algorithm.

Veterinary pathology
Exercise-induced pulmonary hemorrhage (EIPH) is a relevant respiratory disease in sport horses, which can be diagnosed by examination of bronchoalveolar lavage fluid (BALF) cells using the total hemosiderin score (THS). The aim of this study was to e...

Automated interpretation and analysis of bronchoalveolar lavage fluid.

International journal of medical informatics
BACKGROUND: The cytological analysis of bronchoalveolar lavage fluid (BALF) plays an essential role in the differential diagnosis of respiratory diseases. In recent years, deep learning has demonstrated excellent performance in image processing and o...

Defining lower airway bacterial infection in children with chronic endobronchial disorders.

Pediatric pulmonology
BACKGROUND: Differentiating lower airway bacterial infection from possible upper airway contamination in children with endobronchial disorders undergoing bronchoalveolar lavage (BAL) is important for guiding management. A diagnostic bacterial load th...