Prediction of T Stage of Rectal Cancer After Neoadjuvant Therapy by Multi-Parameter Magnetic Resonance Radiomics Based on Machine Learning Algorithms.

Journal: Technology in cancer research & treatment
PMID:

Abstract

INTRODUCTION: Since the response of patients with rectal cancer (RC) to neoadjuvant therapy is highly variable, there is an urgent need to develop accurate methods to predict the post-treatment T (pT) stage. The purpose of this study was to evaluate the utility of multi-parametric MRI radiomics models and identify the most accurate machine learning (ML) algorithms for predicting pT stage of RC.

Authors

  • Tingting Nie
    Department of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Zilong Yuan
    Department of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Yaoyao He
    Department of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Haibo Xu
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650223, Yunnan, China.
  • Xiaofang Guo
    Department of Medical Oncology of the Eastern Hospital, the First Affiliated Hospital, Sun Yat-Sen University, Guangdong, 510700, Guangzhou, China.
  • Yulin Liu
    Department of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.