Altered Blood Oxygen Level-Dependent Signal Stability in the Brain of Patients with Major Depressive Disorder Undergoing Resting-State Functional Magnetic Resonance Imaging.

Journal: Neuropsychobiology
PMID: 39591950

Abstract

INTRODUCTION: Major depressive disorder (MDD) is a common, relapse-prone psychiatric disorder with unknown pathogenesis. Previous studies on resting-state functional magnetic resonance imaging of MDD have mostly focused on the spontaneous activity of blood oxygen level-dependent (BOLD) signals; however, a few studies have investigated BOLD signal stability.

Authors

  • Hao Zheng
    Gilead Sciences, Inc, Foster City, California, USA.
  • Siyu Fan
    Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
  • Xiaonan Pang
    Department of Neurology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
  • Qiang Wei
    School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Yue Wu
    Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China.
  • Yanghua Tian
    4Department of Neurology, The First Hospital of Anhui Medical University, Hefei 230022, P. R. China.
  • Kai Wang
    Department of Rheumatology, The Affiliated Huai'an No. 1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China.

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