Machine learning algorithms using the inflammatory prognostic index for contrast-induced nephropathy in NSTEMI patients.

Journal: Biomarkers in medicine
PMID:

Abstract

Inflammatory prognostic index (IPI), has been shown to be related with poor outcomes in cancer patients. We aimed to investigate the predictive role of IPI for contrast-induced nephropathy (CIN) development in non-ST segment elevation myocardial infarction patients using a nomogram and performing machine learning (ML) algorithms. A total of 178 patients with CIN (+) and 1511 with CIN (-) were included. CIN (+) patients had higher IPI levels, and IPI was independently associated with CIN. A risk prediction nomogram including IPI had a higher predictive ability and good calibration. Naive Bayes and k-nearest neighbors were the best ML algorithms for the prediction of CIN patients. IPI might be used as an easily obtainable marker for CIN prediction using ML algorithms.

Authors

  • Faysal Şaylık
    Health Sciences University, Van Training & Research Hospital, Department of Cardiology, Van, Turkey.
  • Tufan Çınar
    Department of Cardiology, Haydarpasa Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey.
  • Murat Selçuk
    Department of Cardiology, Sancaktepe Education & Research Hospital, Istanbul, 34100, Turkey.
  • İbrahim Halil Tanboğa
    Hisar Intercontinental Hospital, Department of Cardiology, Istanbul, Turkey.