Dalbavancin in-vitro activity obtained against Gram-positive clinical isolates causing bone and joint infections in US and European hospitals (2011-2016).

Journal: International journal of antimicrobial agents
PMID:

Abstract

BACKGROUND: Osteomyelitis is a difficult-to-treat infection that regularly involves prolonged use of systemic antibiotics. Dalbavancin has demonstrated activity against Gram-positive isolates, and has been considered as a candidate for the treatment of osteomyelitis in adults and children. This study evaluated the activity of dalbavancin against pathogens isolated from bone and joint infections (BJI).

Authors

  • Michael A Pfaller
    JMI Laboratories, North Liberty, IA, USA; University of Iowa, Iowa City, IA, USA.
  • Robert K Flamm
    a JMI Laboratories , North Liberty , Iowa , USA.
  • Mariana Castanheira
    a JMI Laboratories , North Liberty , Iowa , USA.
  • Helio S Sader
    a JMI Laboratories , North Liberty , Iowa , USA.
  • Rodrigo E Mendes
    a JMI Laboratories , North Liberty , Iowa , USA.