The escalating global crisis of multidrug-resistant (MDR) bacteria demands innovative strategies that bypass conventional antibiotic limitations. This study introduced a multifunctional Au@CuSe core-shell nanoplatform integrating artificial intellige...
Antimicrobial resistance (AMR) in enterica serotype Kentucky ( Kentucky) is a global challenge, with increasing resistance to cephalosporins, ciprofloxacin, and carbapenems significantly limiting treatment strategies, yet its worldwide dissemination...
Antimicrobial agents and chemotherapy
Oct 31, 2025
While associations of antibiotic resistance traits are not random in multidrug-resistant (MDR) bacteria, clinically relevant resistance patterns remain underexplored. This study used association-set mining to explore resistance associations within i...
Salmonella enterica serovar Typhi, the etiological agent of Typhoid fever, remains a critical public health concern associated with high morbidity in many developing countries. The widespread emergence of multidrug-resistant (MDR) Salmonella Typhi st...
is a highly versatile and resilient pathogen that can infect different tissues and rapidly develop resistance to multiple drugs. Ceftazidime-avibactam (CZA) is an antibiotic often used to treat multidrug-resistant infections; however, the knowledge ...
Hospital-acquired pneumonia (HAP) is prevalent in the neuro-intensive care unit (NICU), significantly increasing susceptibility to infections with multidrug-resistant organisms (MDROs), which result in high mortality rates and substantial healthcare ...
SLAS discovery : advancing life sciences R & D
Apr 9, 2025
BACKGROUND: Antimicrobial resistance (AMR) develops into a worldwide health emergency through genetic and biochemical adaptations which enable microorganisms to resist antimicrobial treatment. β-lactamases (blaNDM, blaKPC) and efflux pumps (MexAB-Opr...
OBJECTIVE: This study aims to construct and compare four machine learning models using the MIMIC-IV database to identify high-risk factors for multidrug-resistant organism (MDRO) infection in Ventilator-associated pneumonia (VAP) patients.
New solutions are needed to detect genotype-phenotype associations involved in microbial drug resistance. Herein, we describe a Group Association Model (GAM) that accurately identifies genetic variants linked to drug resistance and mitigates false-po...
Frontiers in cellular and infection microbiology
Mar 3, 2025
INTRODUCTION: The emergence of foodborne multidrug-resistant (MDR) has attracted considerable global attention. Given that food is the primary transmission route, our study focuses on , a freshwater snail that is commonly consumed as a specialty foo...
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