Evaluating the predictive value of angiogenesis-related genes for prognosis and immunotherapy response in prostate adenocarcinoma using machine learning and experimental approaches.

Journal: Frontiers in immunology
PMID: 38817605

Abstract

BACKGROUND: Angiogenesis, the process of forming new blood vessels from pre-existing ones, plays a crucial role in the development and advancement of cancer. Although blocking angiogenesis has shown success in treating different types of solid tumors, its relevance in prostate adenocarcinoma (PRAD) has not been thoroughly investigated.

Authors

  • Yaxuan Wang
    Department of Computer Science, Rice University, Houston, TX, USA.
  • JiaXing He
    Department of Urology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
  • QingYun Zhao
    Department of Urology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
  • Ji Bo
    Department of Urology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
  • Yu Zhou
    Department of Biospectroscopy, Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany.
  • HaoDong Sun
    Department of Urology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
  • Beichen Ding
    Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • MingHua Ren
    Department of Urology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.

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