AIMC Topic: Angiogenesis
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Developing angiogenesis-related prognostic biomarkers and therapeutic strategies in bladder cancer using deep learning and machine learning.
Scientific reports
Jul 15, 2025
Bladder cancer (BLCA) is a prevalent urological malignancy that exhibits a high degree of tumor heterogeneity and morbidity. Tumor angiogenesis, a vital hallmark of cancer, greatly influences the tumor microenvironment (TME). The emergence of anti-an...
Machine learning model reveals the role of angiogenesis and EMT genes in glioma patient prognosis and immunotherapy.
Biology direct
Nov 12, 2024
Gliomas represent a highly aggressive class of tumors located in the brain. Despite the availability of multiple treatment modalities, the prognosis for patients diagnosed with glioma remains unfavorable. Therefore, further exploration of new biomark...
Evaluating the predictive value of angiogenesis-related genes for prognosis and immunotherapy response in prostate adenocarcinoma using machine learning and experimental approaches.
Frontiers in immunology
May 16, 2024
BACKGROUND: Angiogenesis, the process of forming new blood vessels from pre-existing ones, plays a crucial role in the development and advancement of cancer. Although blocking angiogenesis has shown success in treating different types of solid tumors...
Angio-Net: deep learning-based label-free detection and morphometric analysis of angiogenesis.
Lab on a chip
Feb 13, 2024
Despite significant advancements in three-dimensional (3D) cell culture technology and the acquisition of extensive data, there is an ongoing need for more effective and dependable data analysis methods. These concerns arise from the continued relian...
Vascular persistence following precision micropuncture.
Microcirculation (New York, N.Y. : 1994)
Nov 10, 2023
OBJECTIVE: The success of engineered tissues continues to be limited by time to vascularization and perfusion. Recently, we described a simple microsurgical approach, termed micropuncture (MP), which could be used to rapidly vascularize an adjacently...
Endothelial metabolic zonation in the vascular network: a spatiotemporal blueprint for angiogenesis.
American journal of physiology. Heart and circulatory physiology
Aug 1, 2025
Angiogenesis, a cornerstone of vascular development, tissue regeneration, and tumor progression, is critically orchestrated by the metabolic behavior of endothelial cells (EC). Recent discoveries have redefined EC not as metabolically uniform entitie...
Drug repurposing to identify potential FDA-approved drugs targeting three main angiogenesis receptors through a deep learning framework.
Molecular diversity
Aug 1, 2025
Tumor cell survival depends on the presence of oxygen and nutrients provided by existing blood vessels, particularly when cancer is in its early stage. Along with tumor growth in the vicinity of blood vessels, malignant cells require more nutrients; ...
A machine learning-derived angiogenesis signature for clinical prognosis and immunotherapy guidance in colon adenocarcinoma.
Scientific reports
May 31, 2025
Colon adenocarcinoma (COAD) is one of the most prevalent malignancies worldwide and its prognosis is extremely poor. Angiogenesis has been linked to clinical outcomes, tumor progression, and treatment sensitivity. However, the role of angiogenesis in...
Value of Bioinformatics Models for Predicting Translational Control of Angiogenesis.
Circulation research
May 9, 2025
Angiogenesis, the formation of new blood vessels, is a fundamental biological process with implications for both physiological functions and pathological conditions. While the transcriptional regulation of angiogenesis, mediated by factors such as HI...
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