[The Protective Effect of Tanshinone IIA on Oxygen-glucose Deprivation and Reperfusion Injury of MicrogliaThrough the NLRP3 Inflammatory Signaling Pathway].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

PMID: 28598075

Abstract

OBJECTIVES: To investigate the protective effect of Tanshinone IIA (TSA) on oxygen-glucose deprivation and reperfusion (OGD/R) injury of BV-2 cell and its NLRP3 inflammatory signaling pathway.

Authors

Lin Cai

Department of Anesthesiology, General Hospital of Chengdu Military Region of PLA, Chengdu 610083,China.
Xiao-Bo Yi

Department of Anesthesiology, General Hospital of Chengdu Military Region of PLA, Chengdu 610083,China.
Li-Bang Yuan

Department of Anesthesiology, General Hospital of Chengdu Military Region of PLA, Chengdu 610083,China.
Gu Gong

Department of Anesthesiology, General Hospital of Chengdu Military Region of PLA, Chengdu 610083,China.

Keywords

Abietanes Animals Cell Line Cytokines Glucose Mice Microglia NLR Family, Pyrin Domain-Containing 3 Protein Oxygen Reperfusion Injury Signal Transduction

External Resources

View on PubMed PubMed (28598075)

[The Protective Effect of Tanshinone IIA on Oxygen-glucose Deprivation and Reperfusion Injury of MicrogliaThrough the NLRP3 Inflammatory Signaling Pathway].

Abstract

Authors

Keywords

External Resources

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