[Early Systemic Administration of IL-10 Inhibits Neuropathic Pain in Adult Rats with Tibial Nerve Injury].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
PMID:

Abstract

OBJECTIVES: To determine the effect of early systemic administration of IL-10 on peripheral neuropathic pain induced by tibial nerve permanent transection [modified spared nerve injury (mSNI)]in adult rats.

Authors

  • Ya-Ping Feng
    Department of Histology, Embryology and Neurobiology, West China School of Preclinical and Forensic Medicine, Sichuan University,Chengdu 610041,China.
  • You-Quan Ding
    Department of Histology, Embryology and Neurobiology, West China School of Preclinical and Forensic Medicine, Sichuan University,Chengdu 610041,China.
  • Hong-Yi Ren
    Department of Histology, Embryology and Neurobiology, West China School of Preclinical and Forensic Medicine, Sichuan University,Chengdu 610041,China.
  • Xuan-Yang Li
    Department of Histology, Embryology and Neurobiology, West China School of Preclinical and Forensic Medicine, Sichuan University,Chengdu 610041,China.
  • Yang Qin
    Department of Biochemistry and Molecular Biology, West China School of Preclinical and Forensic Medicine, Sichuan University,Chengdu 610041,China.
  • Jian-Guo Qi
    Department of Histology, Embryology and Neurobiology, West China School of Preclinical and Forensic Medicine, Sichuan University,Chengdu 610041,China.