Differential privacy preserved federated learning for prognostic modeling in COVID-19 patients using large multi-institutional chest CT dataset.

Journal: Medical physics
Published Date:

Abstract

BACKGROUND: Notwithstanding the encouraging results of previous studies reporting on the efficiency of deep learning (DL) in COVID-19 prognostication, clinical adoption of the developed methodology still needs to be improved. To overcome this limitation, we set out to predict the prognosis of a large multi-institutional cohort of patients with COVID-19 using a DL-based model.

Authors

  • Isaac Shiri
    Biomedical and Health Informatics, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Yazdan Salimi
    Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland.
  • Nasim Sirjani
    Research and Development Department, Med Fanavarn Plus Co., Karaj, Iran.
  • Behrooz Razeghi
    Department of Computer Science.
  • Sara Bagherieh
    School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Masoumeh Pakbin
    Imaging Department, Qom University of Medical Sciences, Qum, Iran.
  • Zahra Mansouri
    Department of Biomedical Engineering and Medical Physics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Ghasem Hajianfar
    Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Science, Tehran, Iran.
  • Atlas Haddadi Avval
    School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Dariush Askari
    Department of Radiology Technology, Shahid Beheshti University of Medical, Tehran, Iran.
  • Mohammadreza Ghasemian
    Department of Radiology, Shahid Beheshti Hospital, Qom University of Medical Sciences, Qum, Iran.
  • Saleh Sandoughdaran
    Department of Radiation Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Ahmad Sohrabi
    Radin Makian Azma Mehr Ltd., Radinmehr Veterinary Laboratory, Iran University of Medical Sciences, Gorgan, Iran.
  • Elham Sadati
    Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
  • Somayeh Livani
    Clinical Research Development Unit (CRDU), Sayad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran.
  • Pooya Iranpour
    Medical Imaging Research Center, Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Shahriar Kolahi
    Department of Radiology, School of Medicine, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Bardia Khosravi
    Department of Radiology, Radiology Informatics Lab, Mayo Clinic, Rochester, MN 55905, United States.
  • Salar Bijari
    Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
  • Sahar Sayfollahi
    Department of Neurosurgery, Faculty of Medical Sciences, Iran University of Medical Sciences, Tehran, Iran.
  • Mohammad Reza Atashzar
    Department of Immunology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
  • Mohammad Hasanian
    Department of Radiology, Arak University of Medical Sciences, Arak, Iran.
  • Alireza Shahhamzeh
    Clinical research development center, Qom University of Medical Sciences, Qom, Iran.
  • Arash Teimouri
    Medical Imaging Research Center, Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Neda Goharpey
    Department of radiation oncology, Shohada-e Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Hesamaddin Shirzad-Aski
    Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
  • Jalal Karimi
    Department of Infectious Disease, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
  • Amir Reza Radmard
    Department of Radiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Kiara Rezaei-Kalantari
    Rajaie Cardiovascular, Medical & Research Center, Iran University of Medical Science, Tehran, Iran.
  • Mostafa Ghelich Oghli
    Research and Development Department, Med Fanavarn Plus Co., Karaj, Iran; Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Science, Tehran, Iran. Electronic address: m.g31.mesu@gmail.com.
  • Mehrdad Oveisi
    Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Science, Tehran, Iran; Department of Computer Science, University of British ColumbiaVancouver, BC V6T 1Z4, Canada.
  • Alireza Vafaei Sadr
  • Slava Voloshynovskiy
    Department of Computer Science.
  • Habib Zaidi
    Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva 4, Switzerland. habib.zaidi@hcuge.ch.