The role of cell-free DNA biomarkers and patient data in the early prediction of preeclampsia: an artificial intelligence model.

Journal: American journal of obstetrics and gynecology
PMID:

Abstract

BACKGROUND: Accurate individualized assessment of preeclampsia risk enables the identification of patients most likely to benefit from initiation of low-dose aspirin at 12 to 16 weeks of gestation when there is evidence for its effectiveness, and enables the guidance of appropriate pregnancy care pathways and surveillance.

Authors

  • Asma Khalil
    Department of Obstetrics and Gynaecology, St. George's Hospital, St. George's University of London, London, United Kingdom. Electronic address: asmakhalil79@googlemail.com.
  • Giovanni Bellesia
    Natera Inc., Austin, TX.
  • Mary E Norton
    Department of Obstetrics, Gynecology & Reproductive Sciences, University of California San Francisco, San Francisco, CA.
  • Bo Jacobsson
    Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Sina Haeri
    Austin Maternal-Fetal Medicine, Austin, TX.
  • Melissa Egbert
    Natera Inc., Austin, TX.
  • Fergal D Malone
    Department of Obstetrics and Gynaecology, Rotunda Hospital, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Ronald J Wapner
    Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, NY.
  • Ashley Roman
    Department of Obstetrics and Gynecology, New York University Grossman School of Medicine, New York, NY.
  • Revital Faro
    Department of Obstetrics and Gynecology, Saint Peter's University Hospital, New Brunswick, NJ.
  • Rajeevi Madankumar
    Department of Obstetrics and Gynecology, Long Island Jewish Medical Center, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, NY.
  • Noel Strong
    Department of Obstetrics and Gynecology, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Robert M Silver
    Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT.
  • Nidhi Vohra
    Department of Obstetrics and Gynecology, North Shore University Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY.
  • Jon Hyett
    RPA Women and Babies, Royal Prince Alfred Hospital, Missenden Rd, Camperdown, NSW, 2050, Australia.
  • Cora MacPherson
    Biostatistics Center, George Washington University, Rockville, MD.
  • Brittany Prigmore
    Natera Inc., Austin, TX.
  • Ebad Ahmed
    Natera Inc., Austin, TX.
  • Zachary Demko
    Natera Inc., Austin, TX.
  • J Bryce Ortiz
    Natera Inc., Austin, TX.
  • Vivienne Souter
    Foundation for Healthcare Quality, Seattle, WA USA.
  • Pe'er Dar
    Department of Obstetrics and Gynecology and Women's Health, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY.