Develop and Validate a Nomogram Combining Contrast-Enhanced Spectral Mammography Deep Learning with Clinical-Pathological Features to Predict Neoadjuvant Chemotherapy Response in Patients with ER-Positive/HER2-Negative Breast Cancer.

Journal: Academic radiology
PMID:

Abstract

RATIONALE AND OBJECTIVES: To develop and validate a nomogram that combines contrast-enhanced spectral mammography (CESM) deep learning with clinical-pathological features to predict neoadjuvant chemotherapy (NAC) response (either low Miller Payne (MP-L) grades 1-2 or high MP (MP-H) grades 3-5) in patients with ER-positive/HER2-negative breast cancer.

Authors

  • Dong Xing
  • Yongbin Lv
    Department of Radiology,Yantai Yuhuangding Hospital, Yantai, Shandong 264000 China.
  • Bolin Sun
    Department of Interventional Therapy, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, China.
  • Tongpeng Chu
    Department of Radiology,Yantai Yuhuangding Hospital, Yantai, Shandong 264000 China; Big Data and Artificial Intelligence Lab, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, China.
  • Qianhao Bao
    Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250300, China.
  • Han Zhang
    Johns Hopkins University, Baltimore, MD, USA.