Comparison of ropivacaine with and without fentanyl vs bupivacaine with fentanyl for postoperative epidural analgesia in bilateral total knee replacement surgery.
Journal:
Journal of clinical anesthesia
PMID:
28235533
Abstract
STUDY OBJECTIVES: Pain after total knee replacement (TKR) interferes with early rehabilitation. Although the use of epidural bupivacaine in post-TKR patients is associated with effective analgesia, the associated motor blockade effect delays functional recovery. We compared analgesic efficacy and side effects of postoperative patient-controlled epidural analgesia (PCEA) with plain ropivacaine 0.1% with/without fentanyl 2.5 μg/mL vs plain bupivacaine 0.0625% with fentanyl 2.5 μg/mL in patients undergoing bilateral TKR.
Authors
Keywords
Aged
Amides
Analgesia, Epidural
Analgesia, Patient-Controlled
Analgesics, Opioid
Anesthetics, Local
Arthroplasty, Replacement, Knee
Bupivacaine
Double-Blind Method
Drug Combinations
Female
Fentanyl
Humans
Male
Middle Aged
Nausea
Osteoarthritis
Pain Management
Pain Measurement
Pain, Postoperative
Patient Satisfaction
Postoperative Care
Prospective Studies
Ropivacaine
Treatment Outcome