Machine learning-based response assessment in patients with rectal cancer after neoadjuvant chemoradiotherapy: radiomics analysis for assessing tumor regression grade using T2-weighted magnetic resonance images.

Journal: International journal of colorectal disease
PMID:

Abstract

PURPOSE: This study aimed to assess tumor regression grade (TRG) in patients with rectal cancer after neoadjuvant chemoradiotherapy (NCRT) through a machine learning-based radiomics analysis using baseline T2-weighted magnetic resonance (MR) images.

Authors

  • Yong Dae Lee
    Department of Radiology, Kyung Hee University Hospital, Kyung Hee University College of Medicine, #23 Kyungheedae-ro, Dongdaemun-gu, 02447, Seoul, Republic of Korea.
  • Hyug-Gi Kim
    Department of Biomedical Engineering, Graduate School, Kyung Hee University, 1732, Deogyeong-daero, Giheunggu, Yongin-si, Gyeonggi-do 446-701, Korea.
  • Miri Seo
    Department of Medicine, Kyung Hee University College of Medicine, 23 Kyungheedae-ro, Dongdaemun-gu, 02447, Seoul, Republic of Korea.
  • Sung Kyoung Moon
    Department of Radiology, Kyung Hee University Hospital, Kyung Hee University College of Medicine, #23 Kyungheedae-ro, Dongdaemun-gu, 02447, Seoul, Republic of Korea.
  • Seong Jin Park
    Department of Radiology, Kyung Hee University Hospital, Kyung Hee University College of Medicine, #23 Kyungheedae-ro, Dongdaemun-gu, 02447, Seoul, Republic of Korea.
  • Myung-Won You
    From the Department of Radiology and Research Institute of Radiology (H.J.P., S.Y.K., S.H.P., J.H.B., H.J.K.) and Department of Bioengineering, Asan Medical Institute of Convergence Science and Technology (K.S., S.G.K., N.K.), Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea; and Department of Radiology, Kyung Hee University Hospital, Seoul, Republic of Korea (M.W.Y.).