Hyaluronic Acid Versus Platelet-Rich Plasma: A Prospective, Double-Blind Randomized Controlled Trial Comparing Clinical Outcomes and Effects on Intra-articular Biology for the Treatment of Knee Osteoarthritis.

Journal: The American journal of sports medicine

PMID: 28146403

Abstract

BACKGROUND: The use of platelet-rich plasma (PRP) for the treatment of osteoarthritis (OA) has demonstrated mixed clinical outcomes in randomized controlled trials when compared with hyaluronic acid (HA), an accepted nonsurgical treatment for symptomatic OA. Biological analysis of PRP has demonstrated an anti-inflammatory effect on the intra-articular environment.

Authors

Brian J Cole

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Vasili Karas

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina, USA.
Kristen Hussey

Department of Orthopedics, Rush University Medical Center, Chicago, Illinois, USA.
Kyle Pilz

Department of Orthopedics, Rush University Medical Center, Chicago, Illinois, USA.
Lisa A Fortier

College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.

Keywords

Adult Aged Double-Blind Method Female Humans Hyaluronic Acid Injections, Intra-Articular Lysholm Knee Score Male Middle Aged Osteoarthritis, Knee Pain Measurement Platelet-Rich Plasma Prospective Studies Synovial Fluid Treatment Outcome

External Resources

View on PubMed Access via DOI PubMed (28146403)

Hyaluronic Acid Versus Platelet-Rich Plasma: A Prospective, Double-Blind Randomized Controlled Trial Comparing Clinical Outcomes and Effects on Intra-articular Biology for the Treatment of Knee Osteoarthritis.

Abstract

Authors

Keywords

External Resources

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