AIMC Topic: Synovial Fluid

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Deep learning-based clustering for endotyping and post-arthroplasty response classification using knee osteoarthritis multiomic data.

Annals of the rheumatic diseases Feb 12, 2025
OBJECTIVES: Primary knee osteoarthritis (KOA) is a heterogeneous disease with clinical and molecular contributors. Biofluids contain microRNAs and metabolites that can be measured by omic technologies. Multimodal deep learning is adept at uncovering ...
Treatment Outcome Cluster Analysis Metabolomics Male Middle Aged Deep Learning Synovial Fluid MicroRNAs Arthroplasty, Replacement, Knee Osteoarthritis, Knee Humans Female Aged
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Characterization of clinical data for patient stratification in moderate osteoarthritis with support vector machines, regulatory network models, and verification against osteoarthritis Initiative data.

Scientific reports May 23, 2024
Knee osteoarthritis (OA) diagnosis is based on symptoms, assessed through questionnaires such as the WOMAC. However, the inconsistency of pain recording and the discrepancy between joint phenotype and symptoms highlight the need for objective biomark...
Support Vector Machine Osteoarthritis, Knee Synovial Fluid Middle Aged Gene Regulatory Networks Biomarkers Proteomics Humans Female Aged
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Volumetric quantitative measurement of hip effusions by manual versus automated artificial intelligence techniques: An OMERACT preliminary validation study.

Seminars in arthritis and rheumatism Mar 17, 2021
OBJECTIVE: Preliminary assessment, via OMERACT filter, of manual and automated MRI hip effusion Volumetric Quantitative Measurement (VQM).
Artificial Intelligence Reproducibility of Results Magnetic Resonance Imaging Hip Joint Synovial Fluid Humans
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Superficial Vancomycin Coating of Bone Cement in Orthopedic Revision Surgery: A Safe Technique to Enhance Local Antibiotic Concentrations.

The Journal of arthroplasty Dec 1, 2016
BACKGROUND: The use of antibiotic-loaded cement has become a well-accepted method to develop high local antibiotic concentrations in revision surgery of infected arthroplasty. A new surgical technique has been established to further increase the loca...
Synovial Fluid Prosthesis-Related Infections Humans Anti-Bacterial Agents Gentamicins Female Vancomycin Arthroplasty, Replacement, Hip Powders Aged Arthroplasty, Replacement, Knee Bone Cements Blood Chemical Analysis Male Administration, Topical Reoperation
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Hyaluronic Acid Versus Platelet-Rich Plasma: A Prospective, Double-Blind Randomized Controlled Trial Comparing Clinical Outcomes and Effects on Intra-articular Biology for the Treatment of Knee Osteoarthritis.

The American journal of sports medicine Oct 21, 2016
BACKGROUND: The use of platelet-rich plasma (PRP) for the treatment of osteoarthritis (OA) has demonstrated mixed clinical outcomes in randomized controlled trials when compared with hyaluronic acid (HA), an accepted nonsurgical treatment for symptom...
Synovial Fluid Middle Aged Treatment Outcome Injections, Intra-Articular Pain Measurement Double-Blind Method Aged Humans Osteoarthritis, Knee Hyaluronic Acid Adult Prospective Studies Platelet-Rich Plasma Lysholm Knee Score Female Male
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[Machine learning models established to distinguish OA and RA based on immune factors in the knee joint fluid].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology Apr 1, 2025
Objective Based on 25 indicators including immune factors, cell count classification, and smear results of the knee joint fluid, machine learning models were established to distinguish between osteoarthritis (OA) and rheumatoid arthritis (RA). Method...
Humans Machine Learning Diagnosis, Differential Knee Joint Middle Aged Synovial Fluid Female Osteoarthritis, Knee ROC Curve Aged Arthritis, Rheumatoid Male
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An objective diagnosis of gout and calcium pyrophosphate deposition disease with machine learning of Raman spectra acquired in a point-of-care setting.

Rheumatology (Oxford, England) Apr 1, 2025
OBJECTIVE: Raman spectroscopy is proposed as a next-generation method for the identification of monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals in synovial fluid. As the interpretation of Raman spectra requires specific expertise, the...
Humans Male Machine Learning Point-of-Care Systems Middle Aged Female Gout Aged Spectrum Analysis, Raman Adult Chondrocalcinosis Uric Acid Calcium Pyrophosphate Synovial Fluid
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Is Gelsolin a Biomarker for Aseptic Loosening After Total Knee Arthroplasty?

Journal of long-term effects of medical implants Jan 1, 2015
Gelsolin (GSN) has been implicated in inflammatory reactions in asthmatic patients and may be a marker for acute or chronic reactions in synovial tissue. Detection of increased levels of GSN in synovial fluid could differentiate between aseptic loose...
Humans Biomarkers Cadaver Arthroplasty, Replacement, Knee Gelsolin Prosthesis Failure Reoperation Knee Prosthesis Synovial Fluid
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