Superficial Vancomycin Coating of Bone Cement in Orthopedic Revision Surgery: A Safe Technique to Enhance Local Antibiotic Concentrations.

Journal: The Journal of arthroplasty
PMID: 28111125

Abstract

BACKGROUND: The use of antibiotic-loaded cement has become a well-accepted method to develop high local antibiotic concentrations in revision surgery of infected arthroplasty. A new surgical technique has been established to further increase the local antibiotic concentration and thereby minimizes the risk of reinfection. Our study aim was to investigate the safety of additional superficial vancomycin coating (SVC) by analyzing postoperative joint and serum vancomycin concentrations, as well as the creatinine levels of patients with orthopedic revision surgery.

Authors

  • Florian Amerstorfer
    Department of Orthopedic Surgery, Medical University of Graz, Graz, Austria.
  • Stefan Fischerauer
    Department of Trauma Surgery, Medical University of Graz, Graz, Austria.
  • Patrick Sadoghi
    Department of Orthopedic Surgery, Medical University of Graz, Graz, Austria.
  • Gerold Schwantzer
    Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.
  • Klaus Dieter Kuehn
    Department of Orthopedic Surgery, Medical University of Graz, Graz, Austria.
  • Andreas Leithner
    Department of Orthopedic Surgery, Medical University of Graz, Graz, Austria.
  • Mathias Glehr
    Department of Orthopedic Surgery, Medical University of Graz, Graz, Austria.

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