AIMC Topic: Gentamicins
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Harnessing near-infrared and Raman spectral sensing and artificial intelligence for real-time monitoring and precision control of bioprocess.
Bioresource technology
Feb 7, 2025
Effective monitoring and control of bioprocesses are critical for industrial biomanufacturing. This study demonstrates the integration of near-infrared and Raman spectroscopy for real-time monitoring and precise control of gentamicin fermentation. Th...
A Paradigm of Computer Vision and Deep Learning Empowers the Strain Screening and Bioprocess Detection.
Biotechnology and bioengineering
Jan 16, 2025
High-performance strain and corresponding fermentation process are essential for achieving efficient biomanufacturing. However, conventional offline detection methods for products are cumbersome and less stable, hindering the "Test" module in the ope...
Source Tracing of Kidney Injury via the Multispectral Fingerprint Identified by Machine Learning-Driven Surface-Enhanced Raman Spectroscopic Analysis.
ACS sensors
May 3, 2024
Early diagnosis of drug-induced kidney injury (DIKI) is essential for clinical treatment and intervention. However, developing a reliable method to trace kidney injury origins through retrospective studies remains a challenge. In this study, we desig...
Methyl cellulose/okra mucilage composite films, functionalized with Hypericum perforatum oil and gentamicin, as a potential wound dressing.
International journal of biological macromolecules
Oct 28, 2023
There is a growing demand for the development of functional wound dressings enriched with bioactive natural compounds to improve the quality of life of the population by accelerating the healing process of chronic wounds. In this regard, a functional...
Optimizing Lipofectamine LTX Complex and G-418 Concentration for Improvement of Transfection Efficiency in Human Mesenchymal Stem Cells.
Archives of Razi Institute
Nov 30, 2021
Conventional cancer therapies, including surgery, radiotherapy, and chemotherapy, are not tumor site-specific and have cytotoxic and harmful side effects for normal cells. Mesenchymal stem cells (MSCs), due to their tumor-tropism migration property, ...
A deep learning approach to quantify auditory hair cells.
Hearing research
Jul 22, 2021
Hearing loss affects millions of people worldwide. Yet, there are still no curative therapies for sensorineural hearing loss. Frequent causes of sensorineural hearing loss are due to damage or loss of the sensory hair cells, the spiral ganglion neuro...
Superficial Vancomycin Coating of Bone Cement in Orthopedic Revision Surgery: A Safe Technique to Enhance Local Antibiotic Concentrations.
The Journal of arthroplasty
Dec 1, 2016
BACKGROUND: The use of antibiotic-loaded cement has become a well-accepted method to develop high local antibiotic concentrations in revision surgery of infected arthroplasty. A new surgical technique has been established to further increase the loca...
Machine learning for identifying resistance features of using whole-genome sequence single nucleotide polymorphisms.
Journal of medical microbiology
Nov 1, 2021
, a gram-negative bacterium, is a common pathogen causing nosocomial infection. The drug-resistance rate of is increasing year by year, posing a severe threat to public health worldwide. has been listed as one of the pathogens causing the global c...
[Gene optimization and efficient expression of Trichoderma reesei Cel5A in Pichia pastoris].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Oct 25, 2016
Deficient activity of endo-1,4-beta-glucanase II (Cel5A) secreted by Trichoderma reesei is one of the challenges involved in effective cellulase saccharification of cellulosic substrates. Therefore, we expressed Cel5A in Pichia pastoris by constructi...
Protective Effect of Ginkgo Biloba Extract on Gentamicin-Induced Structural Changes of Calcite-Gelatin Composite.
The journal of international advanced otology
Dec 1, 2015
OBJECTIVE: To evaluate the protective effect of Ginkgo biloba extract (GBE) on gentamicin (GM)-induced morphological damage of an artificial otoconia.
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