Apoptosis and NETotic cell death affect diabetic nephropathy independently: An study integrative study encompassing bioinformatics, machine learning, and experimental validation.

Journal: Genomics
PMID: 38851464

Abstract

OBJECTIVE: Although programmed cell death (PCD) and diabetic nephropathy (DN) are intrinsically conneted, the interplay among various PCD forms remains elusive. In this study, We aimed at identifying independently DN-associated PCD pathways and biomarkers relevant to the related pathogenesis.

Authors

  • Huilian Cai
    Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
  • Yi Zeng
    Department of Geriatrics, Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
  • Dongqiang Luo
    The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Ying Shao
  • Manting Liu
    Clifford Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Jiayu Wu
    Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
  • Xiaolu Gao
    Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
  • Jiyuan Zheng
    Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
  • Lisi Zhou
    Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
  • Feng Liu
    Department of Vascular and Endovascular Surgery, The First Medical Center of Chinese PLA General Hospital, 100853 Beijing, China.

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