AIMC Topic: Diabetic Nephropathies
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Case-control study combined with machine learning techniques to identify key genetic variations in GSK3B that affect susceptibility to diabetic kidney diseases.
BMC endocrine disorders
Jun 5, 2025
The role of genetic susceptibility in early warning and precise treatment of diabetic kidney disease (DKD) requires further investigation. A case-control study was conducted to evaluate the predictive effect of GSK3B genetic polymorphisms on the susc...
Machine learning based identification of anoikis related gene classification patterns and immunoinfiltration characteristics in diabetic nephropathy.
Scientific reports
May 1, 2025
Anoikis and immune cell infiltration are pivotal factors in the pathophysiological mechanism of diabetic nephropathy (DN), yet a comprehensive understanding of the mechanism is lacking. This work aimed to pinpoint distinctive anoikis-related genes (A...
Comparison of artificial intelligence-generated and physician-generated patient education materials on early diabetic kidney disease.
Frontiers in endocrinology
Apr 22, 2025
BACKGROUND: Diabetic kidney disease (DKD) is a common and serious complication of diabetes mellitus and has become the most important cause of end-stage renal disease (ESRD). In light of the rising prevalence of diabetes, there is a growing imperativ...
Machine learning algorithms for diabetic kidney disease risk predictive model of Chinese patients with type 2 diabetes mellitus.
Renal failure
Apr 7, 2025
BACKGROUND: Diabetic kidney disease (DKD) is a common and serious complication of diabetic mellitus (DM). More sensitive methods for early DKD prediction are urgently needed. This study aimed to set up DKD risk prediction models based on machine lear...
Identification of biomarkers related to iron death in diabetic kidney disease based on machine learning algorithms.
Annals of human biology
Apr 2, 2025
BACKGROUND: While ferroptosis has been recognised for its key role in tumour development, its involvement in DKD is not well understood. Identifying differentially expressed ferroptosis-related genes (DEIRGs) could help improve early diagnosis and tr...
Machine-learning assisted discovery unveils novel interplay between gut microbiota and host metabolic disturbance in diabetic kidney disease.
Gut microbes
Mar 6, 2025
Diabetic kidney disease (DKD) is a serious healthcare dilemma. Nonetheless, the interplay between the functional capacity of gut microbiota and their host remains elusive for DKD. This study aims to elucidate the functional capability of gut microbio...
Machine learning-based risk predictive models for diabetic kidney disease in type 2 diabetes mellitus patients: a systematic review and meta-analysis.
Frontiers in endocrinology
Mar 3, 2025
BACKGROUND: Machine learning (ML) models are being increasingly employed to predict the risk of developing and progressing diabetic kidney disease (DKD) in patients with type 2 diabetes mellitus (T2DM). However, the performance of these models still ...
Identification and validation of glycolysis-related diagnostic signatures in diabetic nephropathy: a study based on integrative machine learning and single-cell sequence.
Frontiers in immunology
Jan 23, 2025
BACKGROUND: Diabetic nephropathy (DN) is a complication of systemic microvascular disease in diabetes mellitus. Abnormal glycolysis has emerged as a potential factor for chronic renal dysfunction in DN. The current lack of reliable predictive biomark...
Machine learning-driven Raman spectroscopy: A novel approach to lipid profiling in diabetic kidney disease.
Nanomedicine : nanotechnology, biology, and medicine
Jan 22, 2025
Diabetes mellitus is a chronic metabolic disease that increasingly affects people every year. It is known that with its progression and poor management, metabolic changes can lead to organ dysfunctions, including kidneys. The study aimed to combine R...
Uncovering glycolysis-driven molecular subtypes in diabetic nephropathy: a WGCNA and machine learning approach for diagnostic precision.
Biology direct
Jan 21, 2025
INTRODUCTION: Diabetic nephropathy (DN) is a common diabetes-related complication with unclear underlying pathological mechanisms. Although recent studies have linked glycolysis to various pathological states, its role in DN remains largely underexpl...
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