New vision of HookEfficientNet deep neural network: Intelligent histopathological recognition system of non-small cell lung cancer.

Journal: Computers in biology and medicine
Published Date:

Abstract

BACKGROUND: Efficient and precise diagnosis of non-small cell lung cancer (NSCLC) is quite critical for subsequent targeted therapy and immunotherapy. Since the advent of whole slide images (WSIs), the transition from traditional histopathology to digital pathology has aroused the application of convolutional neural networks (CNNs) in histopathological recognition and diagnosis. HookNet can make full use of macroscopic and microscopic information for pathological diagnosis, but it cannot integrate other excellent CNN structures. The new version of HookEfficientNet is based on a combination of HookNet structure and EfficientNet that performs well in the recognition of general objects. Here, a high-precision artificial intelligence-guided histopathological recognition system was established by HookEfficientNet to provide a basis for the intelligent differential diagnosis of NSCLC.

Authors

  • Huijie Yuan
    College of Public Health, Zhengzhou University, Zhengzhou, 450001, China.
  • Toshitaka Kido
    KYOCERA Communication Systems Co., Ltd, Kyoto, Japan.
  • Masayuki Hirata
    Department of Neurosurgery, Osaka University Graduate School of Medicine.
  • Kengo Ueno
    Corporate R&D Department, KYOCERA Communication Systems Co., Ltd, Kyoto, Japan.
  • Yuji Imai
    KYOCERA Communication Systems (Shanghai) Co., Ltd, Shanghai, China.
  • Kangxuan Chen
    KYOCERA Communication Systems (Shanghai) Co., Ltd, Shanghai, China.
  • Wujie Ren
    Henan 863 Software Co., Ltd, Zhengzhou, China.
  • Liang Yang
  • Kuisheng Chen
    The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
  • Lingbo Qu
    College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
  • Yongjun Wu
    Department of Health Toxicology, College of Public Health, Zhengzhou University, Zhengzhou, China. wuyongjun@zzu.edu.cn.