European journal of hospital pharmacy : science and practice
Mar 18, 2017
The stability of colistin methanesulfonate (CMS) was determined in quadruplicate in elastomeric home infusion pumps containing 1, 2 or 3 MU CMS and in infusion bags with 2 MU CMS all in 100 mL normal saline. Infusions were stored at room temperature ...
European journal of hospital pharmacy : science and practice
Jan 13, 2017
BACKGROUND: Trisodium citrate is an interesting alternative to heparin for the prevention of circuit clotting during extracorporeal procedures, but some protocols require non-commercially available citrate concentrations. Little published information...
European journal of hospital pharmacy : science and practice
Jan 13, 2017
OBJECTIVES: To evaluate the critical quality attributes that might affect the stability of an infliximab biosimilar (SB2, Flixabi) when reconstituted or diluted and stored under refrigeration and at room temperature.
European journal of hospital pharmacy : science and practice
Jan 4, 2017
BACKGROUND: Children often need to be administered very small volumes of medicines that are authorised for use in adults. Neonatal drug delivery is particularly challenging, and doses are often immeasurable with the equipment currently available.
European journal of hospital pharmacy : science and practice
Nov 25, 2016
OBJECTIVES: To evaluate the microbiological and physicochemical compatibility of commonly used proton pump inhibitors (PPIs) esomeprazole, lansoprazole, omeprazole and pantoprazole compounded at a single concentration using SyrSpend SF Alka and store...
European journal of hospital pharmacy : science and practice
Oct 17, 2016
OBJECTIVES: The study evaluated the stability of three combinations of oxycodone and ketamine diluted in normal saline (NS) after storage for 7 days at 23°C and exposed to light.
European journal of hospital pharmacy : science and practice
Oct 12, 2016
INTRODUCTION: An international alert from Becton Dickinson (BD) has noted the possibility of interaction between several molecules and some syringes. The Centralized IntraVenous Additives Service of the institution was using 3 mL BD syringes to store...
European journal of hospital pharmacy : science and practice
Jun 24, 2016
The ubiquitous is an important and troublesome pathogen of nosocomial infection. Multidrug-resistant meningitis is very difficult to treat, usually with high mortality. The disease is generally associated with craniotomy, but rarely with lumbar pun...
European journal of hospital pharmacy : science and practice
Jun 15, 2016
BACKGROUND: Statins are the first-line therapy for lowering high lipid levels. Atorvastatin calcium (AtC) is the most commonly prescribed statin. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase which converts HMG-CoA into mevalo...
European journal of hospital pharmacy : science and practice
Apr 13, 2016
OBJECTIVES: To determine the feasibility of preparing a long-term stable ready-to-use parenteral amiodarone formulation using cyclodextrins as dissolution enhancer.