AI Medical Compendium Journal:
Journal of clinical pharmacology

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Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib.

Journal of clinical pharmacology
Fruquintinib (FRUZAQLA) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (-1, -2, and -3). Two Phase 1, open-label, single-dose studies investigated the impact of hepatic or renal impairment on...

Novel method to predict body weight in children based on age and morphological facial features.

Journal of clinical pharmacology
A new and novel approach of predicting the body weight of children based on age and morphological facial features using a three-layer feed-forward artificial neural network (ANN) model is reported. The model takes in four parameters, including age-ba...

Natural History and Real-World Data in Rare Diseases: Applications, Limitations, and Future Perspectives.

Journal of clinical pharmacology
Rare diseases represent a highly heterogeneous group of disorders with high phenotypic and genotypic diversity within individual conditions. Due to the small numbers of people affected, there are unique challenges in understanding rare diseases and d...