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beta-Globins

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Profiling of 35 Cases of Hb S/Hb E (: c.20A>T/: c.79G>a), Disease and Association with α-Thalassemia and β-Globin Gene Cluster Haplotypes from Odisha, India.

Hemoglobin
Hb S/Hb E (: c.20A>T/: c.79G>A) is an uncommon variant of sickle cell disease resulting from coinheritance of Hb S and Hb E. Clinico-hematological and biochemical parameters of 35 cases of Hb S/Hb E disease were studied and compared with 70 matched c...

Prediction of K562 Cells Functional Inhibitors Based on Machine Learning Approaches.

Current pharmaceutical design
BACKGROUND: β thalassemia is a common monogenic genetic disease that is very harmful to human health. The disease arises is due to the deletion of or defects in β-globin, which reduces synthesis of the β-globin chain, resulting in a relatively excess...