AIMC Topic: Bioreactors
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Intelligent FA/FNA alternating strategy for nitrite-oxidizing bacteria inhibition: Data-driven prediction and process control.
Journal of environmental management
Jun 1, 2025
Alternating treatment with free ammonia (FA) and free nitrous acid (FNA) is an effective strategy to inhibit nitrite-oxidizing bacteria (NOB) in partial nitrification (PN) process. However, the current alternating treatment relies on manual assessmen...
Machine learning assisted media optimization for enhanced insulin production in Pseudomonas fluorescens cell factory and scale-up studies.
International journal of biological macromolecules
Jun 1, 2025
Diabetes mellitus, a chronic metabolic disorder, is characterized by high blood glucose levels. External insulin administration, along with diet and exercise, is recommended to the patients. The increase in the number of diabetics and the adoption of...
Recognizing the state of aerobic granular sludge over its life-cycle in a continuous-flow membrane bioreactor with an artificial intelligence approach.
Journal of environmental management
Jun 1, 2025
The continuous-flow aerobic granular sludge-membrane bioreactor (AGS-MBR) system represents an efficient and sustainable technology for wastewater treatment. AGS, a spherical or ellipsoidal granular sludge formed through microbial self-aggregation un...
Deep-learning-assisted medium optimization improves hyaluronic acid production by Streptococcus zooepidemicus.
Journal of bioscience and bioengineering
Jun 1, 2025
To improve the efficiency of hyaluronic acid production by Streptococcus zooepidemicus, the growth medium was optimized with a pipeline involving a deep learning (DL) algorithm. To train the DL model, the initial training dataset (OA01-18) was design...
Predicting Membrane Fouling of Submerged Membrane Bioreactor Wastewater Treatment Plants Using Machine Learning.
Environmental science & technology
May 27, 2025
Membrane fouling remains a significant challenge in the operation of membrane bioreactors (MBRs). Plant operators rely heavily on observations of filtration performance from noisy sensor data to assess membrane fouling conditions and lab-based protoc...
Machine learning-assisted prediction and identification of key factors affecting nitrogen metabolism for aerobic granular sludge.
Environmental research
May 15, 2025
To achieve higher denitrification efficiency with reduced energy consumption in aerobic granular sludge (AGS) system, a systematic evaluation of the carbon and nitrogen metabolism process for AGS under different stage is essential. Herein, this study...
[Optimization of fermentation processes in intelligent biomanufacturing: on online monitoring, artificial intelligence, and digital twin technologies].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Mar 25, 2025
As a strategic emerging industry, biomanufacturing faces core challenges in achieving precise optimization and efficient scale-up of fermentation processes. This review focuses on two critical aspects of fermentation-real-time sensing and intelligent...
A machine learning-based approach for improving plasmid DNA production in Escherichia coli fed-batch fermentations.
Biotechnology journal
Jun 1, 2024
Artificial Intelligence (AI) technology is spearheading a new industrial revolution, which provides ample opportunities for the transformational development of traditional fermentation processes. During plasmid fermentation, traditional subjective pr...
Evaluation of Lignin-Modifying Enzyme Activity of Trametes spp. (Agaricomycetes) Isolated from Georgian Forests with an Emphasis on T. multicolor Biosynthetic Potential.
International journal of medicinal mushrooms
Jan 1, 2018
In this study, a wide diversity in lignin-modifying enzyme (LME) secretion by 11 Trametes spp. strains isolated from the forests of Georgia was revealed in their submerged cultivation in both synthetic and lignocellulose-based media. Among them, T. m...
An intelligent detecting system for permeability prediction of MBR.
Water science and technology : a journal of the International Association on Water Pollution Research
Jan 1, 2018
The membrane bioreactor (MBR) has been widely used to purify wastewater in wastewater treatment plants. However, a critical difficulty of the MBR is membrane fouling. To reduce membrane fouling, in this work, an intelligent detecting system is develo...
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