AIMC Topic: Culture Media

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Machine learning-led semi-automated medium optimization reveals salt as key for flaviolin production in Pseudomonas putida.

Communications biology Apr 18, 2025
Although synthetic biology can produce valuable chemicals in a renewable manner, its progress is still hindered by a lack of predictive capabilities. Media optimization is a critical, and often overlooked, process which is essential to obtain the tit...
Machine Learning Culture Media Automation Pseudomonas putida Sodium Chloride Synthetic Biology
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Deep Learning-Powered Colloidal Digital SERS for Precise Monitoring of Cell Culture Media.

Nano letters Apr 3, 2025
Maintaining consistent quality in biomanufacturing is essential for producing high-quality complex biologics. Yet, current process analytical technologies (PAT) often fall short in achieving rapid and accurate monitoring of small-molecule critical pr...
Humans Culture Media Deep Learning Colloids Spectrum Analysis, Raman
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Stability of Jurkat cells during short-term liquid storage analyzed by flow imaging microscopy.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V Mar 26, 2025
The viability of cell-based medicinal products (CBMPs) is a critical quality attribute and must be assessed throughout the product lifecycle to contribute to a safe and potent drug product. In this study, we investigated the impact of short-term liqu...
Humans Microscopy Temperature Culture Media Drug Storage Flow Cytometry Cell Survival Jurkat Cells Dimethyl Sulfoxide Time Factors
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Re-imagining human cell culture media: Challenges, innovations, and future directions.

Biotechnology advances Mar 16, 2025
The development of optimized culture media is pivotal to advancements in human cell culture, underpinning progress in regenerative medicine, cell therapies, and personalized medicine. While foundational formulations like Eagle's Minimum Essential Med...
Culture Media Humans Regenerative Medicine Precision Medicine Cell Culture Techniques
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Optimizing the production and efficacy of antimicrobial bioactive compounds from in combating multi-drug-resistant pathogens.

Frontiers in cellular and infection microbiology Jan 6, 2025
BACKGROUND: The rise of antibiotic-resistant pathogens has intensified the search for novel antimicrobial agents. This study aimed to isolate from local soil samples and evaluate its antimicrobial properties, along with optimizing the production of ...
Bacillus subtilis DNA, Bacterial Microbial Sensitivity Tests Anti-Bacterial Agents Spectroscopy, Fourier Transform Infrared Drug Resistance, Multiple, Bacterial Escherichia coli Anti-Infective Agents Culture Media Candida albicans Soil Microbiology Streptomyces Staphylococcus aureus RNA, Ribosomal, 16S
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Extreme learning machine for identifying soil-dwelling microorganisms cultivated on agar media.

Scientific reports Dec 28, 2024
The aim of this research is to create an automated system for identifying soil microorganisms at the genera level based on raw microscopic images of monocultural colonies grown in laboratory environment. The examined genera are: Fusarium, Trichoderma...
Soil Machine Learning Image Processing, Computer-Assisted Culture Media Soil Microbiology Agar
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Data-driven discovery of the interplay between genetic and environmental factors in bacterial growth.

Communications biology Dec 24, 2024
A complex interplay of genetic and environmental factors influences bacterial growth. Understanding these interactions is crucial for insights into complex living systems. This study employs a data-driven approach to uncover the principles governing ...
Gene Expression Regulation, Bacterial Environment Gene-Environment Interaction Escherichia coli Culture Media Machine Learning Gene Regulatory Networks
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Rapid and high accuracy identification of culture medium by CNN of Raman spectra.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Dec 16, 2024
Culture media are widely used for biological research and production. It is essential for the growth of microorganisms, cells, or tissues. It includes complex components like carbohydrates, proteins, vitamins, and minerals. The media's consistency is...
Culture Media Principal Component Analysis Neural Networks, Computer Spectrum Analysis, Raman
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Recent advances in culture medium design for enhanced production of monoclonal antibodies in CHO cells: A comparative study of machine learning and systems biology approaches.

Biotechnology advances Nov 19, 2024
The production of monoclonal antibodies (mAbs) using Chinese Hamster Ovary (CHO) cells has revolutionized the treatment of numerous diseases, solidifying their position as a cornerstone of the biopharmaceutical industry. However, achieving maximum mA...
Machine Learning Animals Culture Media CHO Cells Cell Culture Techniques Cricetulus Systems Biology Antibodies, Monoclonal
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Application of machine learning in in vitro propagation of endemic Lilium akkusianum R. Gämperle.

PloS one Jul 25, 2024
A successful regeneration protocol was developed for micropropagation of Lilium akkusianum R. Gämperle, an endemic species of Türkiye, from scale explants. The study also aimed to evaluate the effects of Meta-Topolin (mT) and N6-Benzyladenine (BA) on...
Culture Media Lilium Plant Growth Regulators Naphthaleneacetic Acids Machine Learning Plant Shoots Regeneration Purines
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