AIMC Topic: Blood Group Antigens

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A deep learning approach to prediction of blood group antigens from genomic data.

Transfusion Sep 13, 2024
BACKGROUND: Deep learning methods are revolutionizing natural science. In this study, we aim to apply such techniques to develop blood type prediction models based on cheap to analyze and easily scalable screening array genotyping platforms.
Humans Neural Networks, Computer Female Male Deep Learning Genomics Genotype Denmark Blood Donors Finland Blood Group Antigens
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Simultaneous phenotyping of five Rh red blood cell antigens on a paper-based analytical device combined with deep learning for rapid and accurate interpretation.

Analytica chimica acta Apr 5, 2022
Both the ABO and Rhesus (Rh) blood groups play crucial roles in blood transfusion medicine. Herein, we report a simple and low-cost paper-based analytical device (PAD) for phenotyping red blood cell (RBC) antigens. Using this Rh typing format, 5 Rh a...
Deep Learning Antibodies Erythrocytes Antigens Rh-Hr Blood-Group System Blood Group Antigens
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Relationship between immunogenicity and protein structure at amino acid substitution sites of blood group antigens.

Blood Jul 24, 2025
Polypeptide blood group antigens, many of which are created by single exofacial amino acid substitutions, have varying immunogenicities. Why some amino acid substitutions are more immunogenic than others is little understood. Using AlphaFold2, an art...
Humans Models, Molecular Protein Conformation Amino Acid Substitution Blood Group Antigens
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