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Erythrocytes

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Effect of PUFAs-ω3 and ω6 on oxidative stress of sheep erythrocytes.

BMC veterinary research
BACKGROUND: In recent years, the use of long-chain polyunsaturated fatty acids (PUFA) ω3 and ω6, as food supplements in livestock has increased due to their beneficial properties related to their antioxidant activity. It has been demonstrated however...

Application of Machine Learning in a Rodent Malaria Model for Rapid, Accurate, and Consistent Parasite Counts.

The American journal of tropical medicine and hygiene
Rodent malaria models serve as important preclinical antimalarial and vaccine testing tools. Evaluating treatment outcomes in these models often requires manually counting parasite-infected red blood cells (iRBCs), a time-consuming process, which can...

An AI-based imaging flow cytometry approach to study erythrophagocytosis.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
Erythrophagocytosis is a process consisting of recognition, engulfment and digestion by phagocytes of antibody-coated or damaged erythrocytes. Understanding the dynamics that are behind erythrophagocytosis is fundamental to comprehend this cellular p...

Neuromorphic-enabled video-activated cell sorting.

Nature communications
Imaging flow cytometry allows image-activated cell sorting (IACS) with enhanced feature dimensions in cellular morphology, structure, and composition. However, existing IACS frameworks suffer from the challenges of 3D information loss and processing ...

Programmable ultrasound-mediated swarms manipulation of bacteria-red blood cell microrobots for tumor-specific thrombosis and robust photothermal therapy.

Trends in biotechnology
Despite the excellent advantages of biomicrorobots, such as autonomous navigation and targeting actuation, effective penetration and retention to deep lesion sites for effective therapy remains a longstanding challenge. Here, we present dual-engine c...

Novel active Trp- and Arg-rich antimicrobial peptides with high solubility and low red blood cell toxicity designed using machine learning tools.

International journal of antimicrobial agents
BACKGROUND: Given the rising number of multidrug-resistant (MDR) bacteria, there is a need to design synthetic antimicrobial peptides (AMPs) that are highly active, non-hemolytic, and highly soluble. Machine learning tools allow the straightforward i...

Assessment of anemia recovery using peripheral blood smears by deep semi-supervised learning.

Annals of hematology
Monitoring anemia recovery is crucial for clinical intervention. Morphological assessment of red blood cells (RBCs) with peripheral blood smears (PBSs) provides additional information beyond routine blood tests. However, the PBS test is labor-intensi...

Deep learning image analysis for continuous single-cell imaging of dynamic processes in Plasmodium falciparum-infected erythrocytes.

Communications biology
Continuous high-resolution imaging of the disease-mediating blood stages of the human malaria parasite Plasmodium falciparum faces challenges due to photosensitivity, small parasite size, and the anisotropy and large refractive index of host erythroc...

Cold storage surpasses the impact of biological age and donor characteristics on red blood cell morphology classified by deep machine learning.

Scientific reports
Assessment of the morphology of red blood cells (RBCs) can improve clinical benefits following blood transfusion. Deep machine learning surpasses traditional microscopy-based classification methods, offering more accurate and consistent results while...

Machine learning-based detection and quantification of red blood cells in Cholistani cattle: A pilot study.

Research in veterinary science
This study presents the first account of using machine learning to detect and count normal and abnormal red blood cells (RBCs), including tear-drop cells and schistocytes, in Cholistani cattle from Pakistan. A Support Vector Machine (SVM) model was a...