AIMC Topic: Connexins

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Identification and validation of PANX1 as an inflammasome-related biomarker in gestational diabetes mellitus: insights from machine learning and experimental approaches.

Mammalian genome : official journal of the International Mammalian Genome Society Jan 16, 2026
Gestational diabetes mellitus (GDM) is characterized by glucose intolerance during pregnancy, resulting from insulin resistance, and is associated with increased maternal and neonatal risks. Inflammasomes play a critical role in GDM pathophysiology b...
Humans Machine Learning Biomarkers Pregnancy Female Adult Nerve Tissue Proteins Placenta Inflammasomes Diabetes, Gestational Connexins
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Application of stochastic automata networks for creation of continuous time Markov chain models of voltage gating of gap junction channels.

BioMed research international Feb 1, 2015
The primary goal of this work was to study advantages of numerical methods used for the creation of continuous time Markov chain models (CTMC) of voltage gating of gap junction (GJ) channels composed of connexin protein. This task was accomplished by...
Humans Neural Networks, Computer Models, Theoretical Markov Chains Ion Channels Connexins Gap Junctions
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