AIMC Topic: COVID-19

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Application of Artificial intelligence in COVID-19-related geriatric care: A scoping review.

Archives of gerontology and geriatrics
BACKGROUND: Older adults have been disproportionately affected by the COVID-19 pandemic. This scoping review aimed to summarize the current evidence of artificial intelligence (AI) use in the screening/monitoring, diagnosis, and/or treatment of COVID...

Harnessing the power of AI: Advanced deep learning models optimization for accurate SARS-CoV-2 forecasting.

PloS one
The pandemic has significantly affected many countries including the USA, UK, Asia, the Middle East and Africa region, and many other countries. Similarly, it has substantially affected Malaysia, making it crucial to develop efficient and precise for...

A computationally-inexpensive strategy in CT image data augmentation for robust deep learning classification in the early stages of an outbreak.

Biomedical physics & engineering express
Coronavirus disease 2019 (COVID-19) has spread globally for over three years, and chest computed tomography (CT) has been used to diagnose COVID-19 and identify lung damage in COVID-19 patients. Given its widespread, CT will remain a common diagnosti...

Artificial intelligence, machine learning and deep learning: Potential resources for the infection clinician.

The Journal of infection
BACKGROUND: Artificial intelligence (AI), machine learning and deep learning (including generative AI) are increasingly being investigated in the context of research and management of human infection.

Topological deep learning based deep mutational scanning.

Computers in biology and medicine
High-throughput deep mutational scanning (DMS) experiments have significantly impacted protein engineering, drug discovery, immunology, cancer biology, and evolutionary biology by enabling the systematic understanding of protein functions. However, t...

Impact of E484Q and L452R Mutations on Structure and Binding Behavior of SARS-CoV-2 B.1.617.1 Using Deep Learning AlphaFold2, Molecular Docking and Dynamics Simulation.

International journal of molecular sciences
During the outbreak of COVID-19, many SARS-CoV-2 variants presented key amino acid mutations that influenced their binding abilities with angiotensin-converting enzyme 2 (hACE2) and neutralizing antibodies. For the B.1.617 lineage, there had been fea...

Exploring the potential of FDA approved anti-diabetic drugs for repurposing against COVID-19: a core combination of multiple computational strategies and integrated artificial intelligence.

Journal of biomolecular structure & dynamics
The latest variant of coronavirus is omicron. The World Health Organization (WHO) designated variation 'B.1.1.529' named omicron as a variant of concern (VOC) on 26 November 2021. By September 2020, it will have infected over 16 million patients and ...

De novo generation of dual-target ligands for the treatment of SARS-CoV-2 using deep learning, virtual screening, and molecular dynamic simulations.

Journal of biomolecular structure & dynamics
De novo generation of molecules with the necessary features offers a promising opportunity for artificial intelligence, such as deep generative approaches. However, creating novel compounds having biological activities toward two distinct targets con...