AIMC Topic: Deinococcus
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Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs.
Nature methods
Sep 23, 2024
Transposon (IS200/IS605)-encoded TnpB proteins are predecessors of class 2 type V CRISPR effectors and have emerged as one of the most compact genome editors identified thus far. Here, we optimized the design of Deinococcus radiodurans (ISDra2) TnpB ...
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