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Rapid microarray-based assay for detection of pyrazinamide resistant Mycobacterium tuberculosis.
Diagnostic microbiology and infectious disease
Dec 30, 2018
Pyrazinamide (PZA) is a key antibiotic for the treatment of drug susceptible tuberculosis. PZA-resistance is mainly mediated by mutations in the pncA gene; however the current gold standard is a phenotypic drug susceptibility test requiring a well-ad...
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