AIMC Topic: Gram-Positive Bacteria

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Improving Recognition of Antimicrobial Peptides and Target Selectivity through Machine Learning and Genetic Programming.

IEEE/ACM transactions on computational biology and bioinformatics
Growing bacterial resistance to antibiotics is spurring research on utilizing naturally-occurring antimicrobial peptides (AMPs) as templates for novel drug design. While experimentalists mainly focus on systematic point mutations to measure the effec...

Nemonoxacin has potent activity against gram-positive, but not gram-negative clinical isolates.

La Clinica terapeutica
OBJECTIVES: The aim of the current study was to analyze the susceptibility of gram-positive and -negative clinical isolates to a novel des-F(6)-quinolone (nemonoxacin) and other selected antimicrobial agents.