AIMC Topic: Gram-Positive Bacteria

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Distribution of main Gram-positive pathogens causing bloodstream infections in United States and European hospitals during the SENTRY Antimicrobial Surveillance Program (2010-2016): concomitant analysis of oritavancin in vitro activity.

Journal of chemotherapy (Florence, Italy) Sep 1, 2018
This study updates the distribution and trends of Gram-positive organisms causing bloodstream infections (BSIs) in the United States (US) and Europe during 2010-2016. In vitro activities of oritavancin and comparators were also evaluated. Staphylococ...
Humans Anti-Bacterial Agents Hospitals Bacteremia United States Europe Cross Infection Gram-Positive Bacteria Gram-Positive Bacterial Infections Lipoglycopeptides
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Improving Recognition of Antimicrobial Peptides and Target Selectivity through Machine Learning and Genetic Programming.

IEEE/ACM transactions on computational biology and bioinformatics Jan 1, 2017
Growing bacterial resistance to antibiotics is spurring research on utilizing naturally-occurring antimicrobial peptides (AMPs) as templates for novel drug design. While experimentalists mainly focus on systematic point mutations to measure the effec...
Neural Networks, Computer Machine Learning Algorithms Drug Design Computational Biology Decision Trees Antimicrobial Cationic Peptides Gram-Negative Bacteria Gram-Positive Bacteria Genetic Engineering
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Nemonoxacin has potent activity against gram-positive, but not gram-negative clinical isolates.

La Clinica terapeutica Jan 1, 2015
OBJECTIVES: The aim of the current study was to analyze the susceptibility of gram-positive and -negative clinical isolates to a novel des-F(6)-quinolone (nemonoxacin) and other selected antimicrobial agents.
Anti-Bacterial Agents Microbial Sensitivity Tests Quinolones Gram-Negative Bacteria Gram-Positive Bacteria
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