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Hemeproteins

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Bayesian models trained with HTS data for predicting β-haematin inhibition and in vitro antimalarial activity.

Bioorganic & medicinal chemistry
A large quantity of high throughput screening (HTS) data for antimalarial activity has become available in recent years. This includes both phenotypic and target-based activity. Realising the maximum value of these data remains a challenge. In this r...

Harnessing the evolutionary information on oxygen binding proteins through Support Vector Machines based modules.

BMC research notes
OBJECTIVES: The arrival of free oxygen on the globe, aerobic life is becoming possible. However, it has become very clear that the oxygen binding proteins are widespread in the biosphere and are found in all groups of organisms, including prokaryotes...

Increasing a microscope's effective field of view via overlapped imaging and machine learning.

Optics express
This work demonstrates a multi-lens microscopic imaging system that overlaps multiple independent fields of view on a single sensor for high-efficiency automated specimen analysis. Automatic detection, classification and counting of various morpholog...