AIMC Topic: Histidine Kinase

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Genome-wide prediction of prokaryotic two-component system networks using a sequence-based meta-predictor.

BMC bioinformatics Sep 18, 2015
BACKGROUND: Two component systems (TCS) are signalling complexes manifested by a histidine kinase (receptor) and a response regulator (effector). They are the most abundant signalling pathways in prokaryotes and control a wide range of biological pro...
ROC Curve Protein Interaction Maps Bacteria Support Vector Machine Area Under Curve Bacterial Proteins Protein Kinases Genome, Bacterial Histidine Kinase
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Bionoi: A Voronoi Diagram-Based Representation of Ligand-Binding Sites in Proteins for Machine Learning Applications.

Methods in molecular biology (Clifton, N.J.) Jan 1, 2021
Bionoi is a new software to generate Voronoi representations of ligand-binding sites in proteins for machine learning applications. Unlike many other deep learning models in biomedicine, Bionoi utilizes off-the-shelf convolutional neural network arch...
Neural Networks, Computer Machine Learning Software Drug Discovery Deep Learning Proteins Ligands Databases, Chemical Binding Sites Histidine Kinase
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