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Histone Deacetylase 6

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PTML Modeling for Alzheimer's Disease: Design and Prediction of Virtual Multi-Target Inhibitors of GSK3B, HDAC1, and HDAC6.

Current topics in medicinal chemistry 32515311
BACKGROUND: Alzheimer's disease is characterized by a progressive pattern of cognitive and functional impairment, which ultimately leads to death. Computational approaches have played an important role in the context of drug discovery for anti-Alzhei...
Alzheimer Disease Drug Design Glycogen Synthase Kinase 3 beta Histone Deacetylase 1 Histone Deacetylase 6 Histone Deacetylase Inhibitors Humans Machine Learning Models, Molecular Molecular Structure Neural Networks, Computer Protein Kinase Inhibitors
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HT_PREDICT: a machine learning-based computational open-source tool for screening HDAC6 inhibitors.

SAR and QSAR in environmental research 39007781
Histone deacetylase 6 (HDAC6) is a promising drug target for the treatment of human diseases such as cancer, neurodegenerative diseases (in particular, Alzheimer's disease), and multiple sclerosis. Considerable attention is paid to the development of...
Drug Evaluation, Preclinical Histone Deacetylase 6 Histone Deacetylase Inhibitors Humans Machine Learning Neural Networks, Computer Quantitative Structure-Activity Relationship Support Vector Machine
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