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Internal Ribosome Entry Sites

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DeepCIP: A multimodal deep learning method for the prediction of internal ribosome entry sites of circRNAs.

Computers in biology and medicine
Circular RNAs (circRNAs) have been found to have the ability to encode proteins through internal ribosome entry sites (IRESs), which are essential RNA regulatory elements for cap-independent translation. Identification of IRES elements in circRNA is ...

DeepIRES: a hybrid deep learning model for accurate identification of internal ribosome entry sites in cellular and viral mRNAs.

Briefings in bioinformatics
The internal ribosome entry site (IRES) is a cis-regulatory element that can initiate translation in a cap-independent manner. It is often related to cellular processes and many diseases. Thus, identifying the IRES is important for understanding its ...

TransRM: Weakly supervised learning of translation-enhancing N6-methyladenosine (mA) in circular RNAs.

International journal of biological macromolecules
As our understanding of Circular RNAs (circRNAs) continues to expand, accumulating evidence has demonstrated that circRNAs can interact with microRNAs and RNA-binding proteins to modulate gene expression. More importantly, a subset of circRNAs has be...