AIMC Topic: RNA, Circular

Clear Filters Showing 1 to 10 of 71 articles

DGCLCMI: a deep graph collaboration learning method to predict circRNA-miRNA interactions.

BMC biology Apr 23, 2025
BACKGROUND: Numerous studies have shown that circRNA can act as a miRNA sponge, competitively binding to miRNAs, thereby regulating gene expression and disease progression. Due to the high cost and time-consuming nature of traditional wet lab experim...
MicroRNAs Humans RNA, Circular Deep Learning Algorithms Computational Biology
View on PubMed DOI

Circular RNA discovery with emerging sequencing and deep learning technologies.

Nature genetics Apr 17, 2025
Circular RNA (circRNA) represents a type of RNA molecule characterized by a closed-loop structure that is distinct from linear RNA counterparts. Recent studies have revealed the emerging role of these circular transcripts in gene regulation and disea...
High-Throughput Nucleotide Sequencing RNA, Circular Single-Cell Analysis Sequence Analysis, RNA Humans Artificial Intelligence Animals Deep Learning Algorithms
View on PubMed DOI

RBPsuite 2.0: an updated RNA-protein binding site prediction suite with high coverage on species and proteins based on deep learning.

BMC biology Mar 11, 2025
BACKGROUND: RNA-binding proteins (RBPs) play crucial roles in many biological processes, and computationally identifying RNA-RBP interactions provides insights into the biological mechanism of diseases associated with RBPs.
Computational Biology RNA-Binding Proteins Software Deep Learning RNA, Circular RNA Binding Sites Humans
View on PubMed DOI

TransRM: Weakly supervised learning of translation-enhancing N6-methyladenosine (mA) in circular RNAs.

International journal of biological macromolecules Feb 27, 2025
As our understanding of Circular RNAs (circRNAs) continues to expand, accumulating evidence has demonstrated that circRNAs can interact with microRNAs and RNA-binding proteins to modulate gene expression. More importantly, a subset of circRNAs has be...
Computational Biology Supervised Machine Learning Humans Translating RNA, Circular Internal Ribosome Entry Sites Adenosine Protein Biosynthesis
View on PubMed DOI

MVGNCDA: Identifying Potential circRNA-Disease Associations Based on Multi-view Graph Convolutional Networks and Network Embeddings.

Interdisciplinary sciences, computational life sciences Feb 17, 2025
Increasing evidences have indicated that circular RNAs play a crucial role in the onset and progression of various diseases. However, exploring potential disease-associated circRNAs using conventional experimental techniques remains both time-intensi...
Algorithms Computational Biology RNA, Circular Humans Neural Networks, Computer
View on PubMed DOI

metaCDA: A Novel Framework for CircRNA-Driven Drug Discovery Utilizing Adaptive Aggregation and Meta-Knowledge Learning.

Journal of chemical information and modeling Feb 12, 2025
In the emerging field of RNA drugs, circular RNA (circRNA) has attracted much attention as a novel multifunctional therapeutic target. Delving deeper into the intricate interactions between circRNA and disease is critical for driving drug discovery e...
RNA, Circular Machine Learning Humans Drug Discovery
View on PubMed DOI

Circular RNA-Drug Association Prediction Based on Multi-Scale Convolutional Neural Networks and Adversarial Autoencoders.

International journal of molecular sciences Feb 11, 2025
The prediction of circular RNA (circRNA)-drug associations plays a crucial role in understanding disease mechanisms and identifying potential therapeutic targets. Traditional methods often struggle to cope with the complexity of heterogeneous network...
Computational Biology Pharmaceutical Preparations Autoencoder RNA, Circular Algorithms Convolutional Neural Networks Humans Neural Networks, Computer
View on PubMed DOI

CellCircLoc: Deep Neural Network for Predicting and Explaining Cell Line-Specific CircRNA Subcellular Localization.

IEEE journal of biomedical and health informatics Feb 10, 2025
The subcellular localization of circular RNAs (circRNAs) is crucial for understanding their functional relevance and regulatory mechanisms. CircRNA subcellular localization exhibits variations across different cell lines, demonstrating the diversity ...
Computational Biology Cell Line RNA, Circular Neural Networks, Computer Deep Learning Humans
View on PubMed DOI

Prediction of circRNA-Disease Associations via Graph Isomorphism Transformer and Dual-Stream Neural Predictor.

Biomolecules Feb 6, 2025
Circular RNAs (circRNAs) have attracted increasing attention for their roles in human diseases, making the prediction of circRNA-disease associations (CDAs) a critical research area for advancing disease diagnosis and treatment. However, traditional ...
MicroRNAs Algorithms Computational Biology RNA, Circular Humans Neural Networks, Computer
View on PubMed DOI

Bimodal In Situ Analyzer for Circular RNA in Extracellular Vesicles Combined with Machine Learning for Accurate Gastric Cancer Detection.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) Jan 17, 2025
Circular RNAs in extracellular vesicles (EV-circRNAs) are gaining recognition as potential biomarkers for the diagnosis of gastric cancer (GC). Most current research is focused on identifying new biomarkers and their functional significance in diseas...
Biomarkers, Tumor RNA, Circular Male Humans Extracellular Vesicles Machine Learning Female Stomach Neoplasms Early Detection of Cancer
View on PubMed DOI
Popular Topics
Recent Journals