AIMC Topic: Maximum Tolerated Dose

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Personalized oncology with artificial intelligence: The case of temozolomide.

Artificial intelligence in medicine Aug 12, 2019
PURPOSE: Using artificial intelligence techniques, we compute optimal personalized protocols for temozolomide administration in a population of patients with variability.
Humans Artificial Intelligence Algorithms Computer Simulation Brain Neoplasms Dose-Response Relationship, Drug Bayes Theorem Models, Biological Tumor Burden Maximum Tolerated Dose Temozolomide
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In silico toxicity profiling of natural product compound libraries from African flora with anti-malarial and anti-HIV properties.

Computational biology and chemistry Dec 6, 2017
This paper describes an analysis of the diversity and chemical toxicity assessment of three chemical libraries of compounds from African flora (the p-ANAPL, AfroMalariaDb, and Afro-HIV), respectively containing compounds exhibiting activities against...
Humans Machine Learning Computer Simulation Africa Anti-HIV Agents Principal Component Analysis Models, Molecular Molecular Structure Antimalarials Datasets as Topic Mutagens Maximum Tolerated Dose Small Molecule Libraries
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