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Microtubule Proteins

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Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility.

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Sperm motility is crucial for successful fertilization. Highly decorated doublet microtubules (DMTs) form the sperm tail skeleton, which propels the movement of spermatozoa. Using cryo-electron microscopy (cryo-EM) and artificial intelligence (AI)-ba...