AIMC Topic: Monosaccharide Transport Proteins

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Identification of Glucose Transport Modulators In Vitro and Method for Their Deep Learning Neural Network Behavioral Evaluation in Glucose Transporter 1-Deficient Mice.

The Journal of pharmacology and experimental therapeutics Jan 12, 2023
Metabolic flux augmentation via glucose transport activation may be desirable in glucose transporter 1 (Glut1) deficiency syndrome (G1D) and dementia, whereas suppression might prove useful in cancer. Using lung adenocarcinoma cells that predominantl...
Humans Animals Deep Learning Mice Glucose Carbohydrate Metabolism, Inborn Errors Glucose Transporter Type 1 Monosaccharide Transport Proteins
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SLC35A2 loss-of-function variants affect glycomic signatures, neuronal fate and network dynamics.

Brain : a journal of neurology Dec 4, 2025
SLC35A2 encodes a uridine diphosphate (UDP)-galactose transporter essential for glycosylation of proteins and galactosylation of lipids and glycosaminoglycans. Germline genetic SLC35A2 variants have been identified in congenital disorders of glycosyl...
Humans Glycosylation Cell Differentiation Neurons Nerve Net Induced Pluripotent Stem Cells Glycomics Loss of Function Mutation Monosaccharide Transport Proteins
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