Mutation, Missense

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mCSM-PPI2: predicting the effects of mutations on protein-protein interactions.

Nucleic acids research Jul 2, 2019
Protein-protein Interactions are involved in most fundamental biological processes, with disease causing mutations enriched at their interfaces. Here we present mCSM-PPI2, a novel machine learning computational tool designed to more accurately predic...
Humans Machine Learning Software Protein Binding Proteins Internet Benchmarking Datasets as Topic Crystallography, X-Ray Binding Sites Thermodynamics Mutation, Missense Protein Interaction Mapping Protein Interaction Domains and Motifs Protein Conformation, alpha-Helical Protein Conformation, beta-Strand
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